The many functions of smc proteins in chromosome dynamics

  title={The many functions of smc proteins in chromosome dynamics},
  author={Rolf Jessberger},
  journal={Nature Reviews Molecular Cell Biology},
Members of the structural maintenance of chromosomes (SMC) family share a characteristic design and configuration of protein domains that provides the molecular basis for the various functions of this family in chromosome dynamics. SMC proteins have a role in chromosome condensation, sister-chromatid cohesion, DNA repair and recombination, and gene dosage compensation, and they function in somatic and meiotic cells. As more is learned about how their unique design affects their function, a… CONTINUE READING

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