The many facets of homologous recombination at telomeres

@inproceedings{Claussin2015TheMF,
  title={The many facets of homologous recombination at telomeres},
  author={Cl{\'e}mence Claussin and Michael Chang},
  booktitle={Microbial cell},
  year={2015}
}
The ends of linear chromosomes are capped by nucleoprotein structures called telomeres. A dysfunctional telomere may resemble a DNA double-strand break (DSB), which is a severe form of DNA damage. The presence of one DSB is sufficient to drive cell cycle arrest and cell death. Therefore cells have evolved mechanisms to repair DSBs such as homologous… CONTINUE READING