The many faces of diabetes: a disease with increasing heterogeneity

@article{Tuomi2014TheMF,
  title={The many faces of diabetes: a disease with increasing heterogeneity},
  author={T. Tuomi and N. Santoro and S. Caprio and Meng-yin Cai and L. Groop},
  journal={The Lancet},
  year={2014},
  volume={383},
  pages={1084-1094}
}
Diabetes is a much more heterogeneous disease than the present subdivision into types 1 and 2 assumes; type 1 and type 2 diabetes probably represent extremes on a range of diabetic disorders. Both type 1 and type 2 diabetes seem to result from a collision between genes and environment. Although genetic predisposition establishes susceptibility, rapid changes in the environment (ie, lifestyle factors) are the most probable explanation for the increase in incidence of both forms of diabetes. Many… Expand
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