The many faces of Th17 cells.

@article{Peters2011TheMF,
  title={The many faces of Th17 cells.},
  author={Anneli Peters and Youjin V Lee and Vijay K Kuchroo},
  journal={Current opinion in immunology},
  year={2011},
  volume={23 6},
  pages={702-6}
}
Th17 cells have been shown to be strong inducers of tissue inflammation and autoimmune diseases. However, not all Th17 cells are pathogenic and increasing data suggest that Th17 cells may come in different flavors. Thus, Th17 cells cannot be described using a narrow schematic, but instead Th17 cells comprise a wide spectrum with a range of effector phenotypes. Here, we review the key factors that generate such diversity, as well as the cytokines and transcription factors that are differentially… CONTINUE READING
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