The mannosidase inhibitors 1-deoxymannojirimycin and swainsonine have no effect on the biosynthesis and infectivity of Rous sarcoma virus.

Abstract

The effects of inhibitors, which interfere with oligosaccharide trimming by blocking mannosidases, on the processing and export of the viral glycoproteins of Rous sarcoma virus (RSV), have been studied. 1-Deoxymannojirimycin (DIM) prevents removal of mannose residues from the Man9 (GlcNAc)2 oligosaccharide whereas swainsonine (SW) blocks at a later stage… (More)

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@article{Bosch1985TheMI, title={The mannosidase inhibitors 1-deoxymannojirimycin and swainsonine have no effect on the biosynthesis and infectivity of Rous sarcoma virus.}, author={Justine Vanden Bosch and A Tlust{\'y} and Wendy McDowell and G{\"{u}nther Legler and Ralph T. Schwarz}, journal={Virology}, year={1985}, volume={143 1}, pages={342-6} }