The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells.

@article{Brouw2009TheMR,
  title={The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells.},
  author={Marjoleine L. Op den Brouw and Rekha S. Binda and Teunis B H Geijtenbeek and Harry L. A. Janssen and Andrea M. Woltman},
  journal={Virology},
  year={2009},
  volume={393 1},
  pages={84-90}
}
Dendritic cells (DC) play a key role in anti-viral immunity. Direct interactions between DC and hepatitis B virus (HBV) may explain the impaired DC function and the ineffective anti-viral response of chronic HBV patients resulting in HBV persistence. Here, the interaction between HBV surface antigens (HBsAg) and DC and the receptor involved were examined by flow cytometry in blood and liver tissue of HBV patients. The in vitro data showed that the mannose receptor (MR) is involved in HBsAg… CONTINUE READING
19 Citations
32 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 32 references

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis

  • M. L. Op den Brouw, R. S. Binda, +4 authors A. M. Woltman
  • B virus. Immunology
  • 2008
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…