The manganese-containing ribonucleotide reductase of Corynebacterium ammoniagenes is a class Ib enzyme.

@article{Fieschi1998TheMR,
  title={The manganese-containing ribonucleotide reductase of Corynebacterium ammoniagenes is a class Ib enzyme.},
  author={Franck Fieschi and Eduard Torrents and Larisa Toulokhonova and Albert Jordan and Ulf Hellman and Jordi Barb{\'e} and Isidre Gibert and Margareta Karlsson and Britt-Marie Sj{\"o}berg},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 8},
  pages={4329-37}
}
Ribonucleotide reductases (RNRs) are key enzymes in living cells that provide the precursors of DNA synthesis. The three characterized classes of RNRs differ by their metal cofactor and their stable organic radical. We have purified to near homogeneity the enzymatically active Mn-containing RNR of Corynebacterium ammoniagenes, previously claimed to represent a fourth RNR class. N-terminal and internal peptide sequence analyses clearly indicate that the C. ammoniagenes RNR is a class Ib enzyme… CONTINUE READING