The management of unicentric and multicentric Castleman's disease: a report of 16 cases and a review of the literature.

@article{Bowne1999TheMO,
  title={The management of unicentric and multicentric Castleman's disease: a report of 16 cases and a review of the literature.},
  author={Wilbur B Bowne and Jonathan J. Lewis and Daniel A Filippa and Rub{\'e}n Niesvizky and Ari D. Brooks and Michael E. Burt and Murray F. Brennan},
  journal={Cancer},
  year={1999},
  volume={85 3},
  pages={706-17}
}
BACKGROUND Castleman's disease (CD), or angiofollicular lymph node hyperplasia, creates both diagnostic and therapeutic dilemmas for most physicians. For patients with this rare and poorly understood disease, the optimal therapy is unknown. The authors report their experience during the years 1986-1997 with this uncommon clinicopathologic entity. METHODS Sixteen patients with a histologic diagnosis of CD were identified in the pathology database. Unicentric disease was defined as a solitary… CONTINUE READING
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