The management of nonmetastatic locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery
@article{Sorace2005TheMO, title={The management of nonmetastatic locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery}, author={R. Sorace and Caroline S. Bagley and Allen S. Lichter and D. Danforth and M. Wesley and Robert C. Young and Marc E. Lippman}, journal={World Journal of Surgery}, year={2005}, volume={9}, pages={775-785} }
Forty-three patients with locally advanced breast cancer, 15 with stage IIIA and 28 with stage IIIB, received primary induction chemotherapy, including hormonal synchronization in 38 patients, to a maximum objective clinical response before proceeding to local therapy. Patients achieving a pathological complete response received radiation therapy, while patients with residual disease, partial response (PR), or no change (NC) status received debulking surgery prior to radiation therapy; in all… CONTINUE READING
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References
SHOWING 1-10 OF 35 REFERENCES
Combined chemotherapy and radiotherapy for locally advanced breast cancer.
- Medicine
- European journal of cancer
- 1980
- 92
Multimodal treatment for locally advanced breast cancer. Result of chemotherapy-radiotherapy versus chemotherapy-surgery.
- Medicine
- Cancer clinical trials
- 1981
- 156
Combined chemotherapy-radiotherapy approach in locally advanced (T3b-T4) breast cancer
- Medicine
- Cancer Chemotherapy and Pharmacology
- 2004
- 151
A randomized attempt to increase the efficacy of cytotoxic chemotherapy in metastatic breast cancer by hormonal synchronization.
- Medicine
- Journal of clinical oncology : official journal of the American Society of Clinical Oncology
- 1984
- 96
- Highly Influential
Natural history and survival of inoperable breast cancer treated with radiotherapy and radiotherapy followed by radical mastectomy
- Medicine
- Cancer
- 1976
- 179
A phase II trial of tamoxifen, premarin, methotrexate and 5-fluorouracil in metastatic breast cancer
- Medicine
- Breast Cancer Research and Treatment
- 2005
- 8