The mammalian centrosome and its functional significance

@article{Schatten2008TheMC,
  title={The mammalian centrosome and its functional significance},
  author={Heide Schatten},
  journal={Histochemistry and Cell Biology},
  year={2008},
  volume={129},
  pages={667 - 686}
}
Primarily known for its role as major microtubule organizing center, the centrosome is increasingly being recognized for its functional significance in key cell cycle regulating events. We are now at the beginning of understanding the centrosome’s functional complexities and its major impact on directing complex interactions and signal transduction cascades important for cell cycle regulation. The centrosome orchestrates entry into mitosis, anaphase onset, cytokinesis, G1/S transition, and… CONTINUE READING
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