Corpus ID: 90846462

The male anti-fertility effects of embelin and some of Its closely related benzoquinones

  title={The male anti-fertility effects of embelin and some of Its closely related benzoquinones},
  author={E. K. Githui},
There is a broad range of biological activities acclaimed to benzoquinones and their derivatives. Verification of these claims awaits solid scientific evaluation. Embelin, a crystalline benzoquinone is extractable from locally available plants viz Embelia schimperi. Rapanea melanphloes. Maesa___ lanceolata and Myrsine africana. Other species of this plant e.g. Embelia ribes occurs widely in the tropical climates. Several reports, originally folkloric but now in scientific papers have been… Expand


Potential value of plants as sources of new antifertility agents I.
The preovulatory, preimplantation, and postIMplantation antifertility mechanisms of plant substances affecting the hypothalamus-pituitary, ovary, oviduct, uterus, or vagina are discussed in terms of reproductive differences among laboratory animal species. Expand
Antifertility effects of Embelia ribes Burm.
Results of studies in female rats of the antifertility effect of Embelia ribes berries its various extracts and embelin the putative active principle are reported; however no dose-duration effect was observed. Expand
Efficacy of Natural Embelin Against the Red Flour Beetle, Tribolium Castaneum Herbst
In the present study, embelin did not exhibit any chemosterilant action or contact toxicity to adult beetles, and its efficacy against Tribolium Castaneum Herbst is discussed. Expand
Physiological effects and metabolism of gossypol.
Gossypol1 is a yellow coloring matter which occurs in various parts of the cotton plant and was induced in response to such irritants as pathogens, metabolic inhibitors, and cupric and mercuric ions. Expand
Antifertility Effects of Embelin in Male Rats
Summary:  Embelin, extracted from Embelia ribes Burm. berries, altered the testicular histology and glycogen, gametogenic counts and accessory sex gland fructose at the dose levels 0.3,0.4 and 0.5Expand
Prospects for higher plants as a source of useful fertility regulating agents for human use.
It appears from the preliminary data that NAPRALERT computer analysis has been able to identify many promising fertility-regulating plants and 8 plants seem to have reproducible post-midcycle fertility-regulation activity following oral administration in a bioassay developed by the WHO Task Force. Expand
Mutagenicity of natural naphthoquinones and benzoquinones in the Salmonella/microsome test.
Results show that natural naphthoquinones are mutagenic when they have only one or two hydroxyl and/or methyl substituents. Expand
Botanical Sources of Fertility Regulating Agents: Chemistry and Pharmacology
This work has gathered information concerning more than 2,000 additional species which might possibly have fertility regulating effects, and cited over 1,300 plant species that might have such activity based on their folkloric reputation, on their chemical constituents, and on the results of their testing in animals. Expand
Studies of the human testis. II. A study of androstenediol and its monosulfate in human testes in vitro.
Time studies showed that androstenediol is an important intermediate for the formation of testosterone from DHA under these in vitro conditions and it is suggested that and Frostenediol-3-sulfate was formed more readily from androstensiol than from either DHA or DHA-Sulfate. Expand
Cyproterone acetate diminishes sexual activity in male rabbits.
  • A. Ǻgmo
  • Biology, Medicine
  • Journal of reproduction and fertility
  • 1975
It was concluded that CA reduced the activity of at least one of the accessory sex glands as well as sexual behaviour in rabbits, lending support to the current hypothesis that the endocrine regulation of rabbit sexual behaviour differs from that of the rat. Expand