The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vδ1 TCR.

Abstract

αβ T-cell lines specific for sulfatide, an abundant myelin glycosphingolipid presented by various CD1 molecules, have been previously derived from PBMCs of patients with demyelinating diseases such as multiple sclerosis (MS) but also from healthy subjects. Using an unbiased tetramer-based MACS enrichment method to enrich for rare antigen-specific cells, we… (More)
DOI: 10.1002/eji.201242531

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@article{Bai2012TheMO, title={The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vδ1 TCR.}, author={Li Bai and Damien Picard and Brian L. Anderson and Vinod A Chaudhary and Adrienne M Luoma and Bana Jabri and Erin J. Adams and P B Savage and Albert Bendelac}, journal={European journal of immunology}, year={2012}, volume={42 9}, pages={2505-10} }