The major surface glycoprotein expression sites of two special forms of rat Pneumocystis carinii differ in structure.

@article{Schaffzin2000TheMS,
  title={The major surface glycoprotein expression sites of two special forms of rat Pneumocystis carinii differ in structure.},
  author={Joshua K. Schaffzin and James R. Stringer},
  journal={The Journal of infectious diseases},
  year={2000},
  volume={181 5},
  pages={1729-39}
}
Pneumocystis carinii forma specialis carinii has a unique locus called the UCS, which controls surface antigen variation by acting as the expression site for a family of genes encoding isoforms of the major surface glycoprotein (MSG). Every MSG mRNA begins with 380 nucleotides copied from the UCS locus. This UCS leader sequence is necessary for initiation of translation and for protein processing. Given the UCS's importance in P. carinii f. sp. carinii, it was of interest to examine the UCS… CONTINUE READING

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