The major inflammatory mediator interleukin-6 and obesity

@article{der2009TheMI,
  title={The major inflammatory mediator interleukin-6 and obesity},
  author={Katalin {\'E}der and Noemi J. Baffy and Andr{\'a}s Falus and Andras Kristof Fulop},
  journal={Inflammation Research},
  year={2009},
  volume={58},
  pages={727-736}
}
Adipose tissue is one of the main sources of inflammatory mediators, with interleukin-6 (IL-6) among them. Although high systemic levels of inflammatory mediators are cachectogenic and/or anorexic, today it is a widely propagated thesis that in the background of obesity, a low level of chronic inflammation can be found, with IL-6 being one of the many suggested mediators. This paper reviews the studies describing elevated IL-6 levels in obese patients and the role of adipocytes and adipose… CONTINUE READING
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