The major histocompatibility complex gene region and sarcoidosis susceptibility in African Americans.

@article{Rybicki2003TheMH,
  title={The major histocompatibility complex gene region and sarcoidosis susceptibility in African Americans.},
  author={Benjamin A Rybicki and Mary J Maliarik and Laila M. Poisson and Roberta Sheffer and Kang Mei Chen and Marcie L Major and Gary A. Chase and Michael C. Iannuzzi},
  journal={American journal of respiratory and critical care medicine},
  year={2003},
  volume={167 3},
  pages={444-9}
}
Investigators have intensively evaluated the major histocompatibility (MHC) complex for sarcoidosis susceptibility genes with the majority of reports implicating the human leukocyte antigen (HLA)-DRB1 gene. Because most studies have been performed in white and Asian populations, we sought to determine which MHC genes might be risk factors for sarcoidosis in African Americans. We genotyped six microsatellite markers spanning 11.6 megabases that overlapped the MHC region on chromosome 6p21-22 in… CONTINUE READING

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