The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene.

@article{Galvin1992TheMH,
  title={The major histocompatibility complex class I antigen-binding protein p88 is the product of the calnexin gene.},
  author={Kerri Galvin and Sandeep Krishna and Frederique Ponchel and Mark Walter Frohlich and David E. Cummings and Raul Carlson and Jack R Wands and Kurt J Isselbacher and S. C. Pillai and Mehmet Fatih Ozturk},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 18},
  pages={8452-6}
}
A 90-kDa phosphoprotein (p90) of the endoplasmic reticulum was identified by a monoclonal antibody generated against human hepatoma cells. Pulse-chase experiments with [32P]phosphate and [35S]methionine demonstrated that p90 formed both stable and transient complexes with other cellular proteins, suggesting its role as a molecular chaperone. This protein associates with heavy chains of major histocompatibility complex class I proteins, suggesting that it is the human homolog of the recently… CONTINUE READING

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