• DOI:10.1038/s41586-020-2818-3
Corpus ID: 222148977

The major genetic risk factor for severe COVID-19 is inherited from Neanderthals

@article{Zeberg2020TheMG,
  title={The major genetic risk factor for severe COVID-19 is inherited from Neanderthals},
  author={H. Zeberg and S. P{\"a}{\"a}bo},
  journal={Nature},
  year={2020},
  pages={1-3}
}

• H. Zeberg, S. Pääbo
• Published 2020
• Medicine
• Nature

A recent genetic association study 1 identified a gene cluster on chromosome 3 as a risk locus for respiratory failure after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A separate study (COVID-19 Host Genetics Initiative) 2 comprising 3,199 hospitalized patients with coronavirus disease 2019 (COVID-19) and control individuals showed that this cluster is the major genetic risk factor for severe symptoms after SARS-CoV-2 infection and hospitalization. Here we show… Expand