The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo.

@article{Huang2008TheMR,
  title={The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo.},
  author={Wei Huang and Xin Li and Elizabeth A. Morris and Luminita Alina Tudorica and Venkatraman E. Seshan and William D. Rooney and Ian J. Tagge and Ya Wang and Jingang Xu and Charles S. Springer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2008},
  volume={105 46},
  pages={17943-8}
}
The pharmacokinetic analysis of dynamic-contrast-enhanced (DCE) MRI data yields K(trans) and k(ep), two parameters independently measuring the capillary wall contrast reagent transfer rate. The almost universally used standard model (SM) embeds the implicit assumption that equilibrium transcytolemmal water exchange is effectively infinitely fast. In analyses of routine DCE-MRI data from 22 patients with suspicious breast lesions initially ruled positive by institutional screening protocols, the… CONTINUE READING

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