The magic of the hypoxia-signaling cascade

@article{Benizri2008TheMO,
  title={The magic of the hypoxia-signaling cascade},
  author={Emmanuel Isaac Benizri and Amandine Ginouv{\`e}s and Edurne Berra},
  journal={Cellular and Molecular Life Sciences},
  year={2008},
  volume={65},
  pages={1133-1149}
}
Abstract.All organisms respond to changes in their environment by activating complex signaling cascades. The “hypoxia-signaling cascade” is activated in response to low oxygen availability and this activation is central to maintaining oxygen homeostasis and hence to survival. By regulating the transcriptional complex hypoxia-inducible factor, hypoxia is associated with several physiopathological processes. Several strategies, based on the targeting of the hypoxia-signaling cascade, have been… CONTINUE READING

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