The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis.

@article{Bode2012TheMR,
  title={The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis.},
  author={Johannes G. Bode and Christian Ehlting and Dieter H{\"a}ussinger},
  journal={Cellular signalling},
  year={2012},
  volume={24 6},
  pages={
          1185-94
        }
}
In macrophages detection of gram-negative bacteria particularly involves binding of the outer-wall component lipopolysaccharide (LPS) to its cognate receptor complex, comprising Toll like receptor 4 (TLR4), CD14 and MD2. LPS-induced formation of the LPS receptor complex elicits a signaling network, including intra-cellular signal-transduction directly activated by the TLR4 receptor complex as well as successional induction of indirect autocrine and paracrine signaling events. All these… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 122 CITATIONS

FILTER CITATIONS BY YEAR

2012
2019

CITATION STATISTICS

  • 13 Highly Influenced Citations

  • Averaged 20 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 114 REFERENCES

D

  • C. Ehlting, N. Ronkina, +6 authors M. Gaestel
  • Häussinger, J.G. Bode, Journal of Biological…
  • 2011
Highly Influential
21 Excerpts

G

  • S. S. Iyer, A. A. Ghaffari
  • Cheng, Journal of Immunology 185
  • 2010
Highly Influential
10 Excerpts

P

  • B. Schaljo, F. Kratochvill, +10 authors P. J. Murray
  • Kovarik, Journal of Immunology 183
  • 2009
Highly Influential
4 Excerpts

S

  • T. Kawai
  • Akira, International Immunology 21
  • 2009
Highly Influential
16 Excerpts

R

  • J. C. Kagan, T. Su, T. Horng, A. Chow, S. Akira
  • Medzhitov, Nature Immunology 9
  • 2008
Highly Influential
7 Excerpts

Y

  • E. Seki, S. De Minicis, C. H. Osterreicher, J. Kluwe
  • Osawa, D.A. Brenner, R.F. Schwabe, Nature…
  • 2007
Highly Influential
6 Excerpts

M

  • T. Raabe
  • Bukrinsky, R.A. Currie, Journal of Biological…
  • 1998
Highly Influential
9 Excerpts

J

  • H. Louis, O. Le Moine, M. O. Peny, B. Gulbis, F. Nisol, M. Goldman
  • Deviere, Gastroenterology 112
  • 1997
Highly Influential
8 Excerpts

Nature Reviews

  • A. Yoshimura, T. Naka, M. Kubo
  • Immunology 7
  • 2007
Highly Influential
5 Excerpts

T

  • R. Z. Murray, F. G. Wylie
  • Khromykh, D.A. Hume, J.L. Stow, Journal of…
  • 2005
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…