The machinery of local Ca2+ signalling between sarco-endoplasmic reticulum and mitochondria.

Abstract

Growing evidence suggests that propagation of cytosolic [Ca2+] ([Ca2+]c) spikes and oscillations to the mitochondria is important for the control of fundamental cellular functions. Delivery of [Ca2+]c spikes to the mitochondria may utilize activation of the mitochondrial Ca2+ uptake sites by the large local [Ca2+]c rise occurring in the vicinity of… (More)

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Cite this paper

@article{Hajnczky2000TheMO, title={The machinery of local Ca2+ signalling between sarco-endoplasmic reticulum and mitochondria.}, author={Gy{\"{o}rgy Hajn{\'o}czky and Gy{\"{o}rgy Csord{\'a}s and Muniswamy Madesh and Pal Pacher}, journal={The Journal of physiology}, year={2000}, volume={529 Pt 1}, pages={69-81} }