The mRNA levels of GtH Iβ, GtH IIβ and GH in relation to testicular development and testosterone treatment in pituitary cells of male tilapia

@article{Melamed2004TheML,
  title={The mRNA levels of GtH Iβ, GtH IIβ and GH in relation to testicular development and testosterone treatment in pituitary cells of male tilapia},
  author={Philippa Melamed and Gal Gur and Hanna Rosenfeld and Abigail Elizur and Zvi Yaron},
  journal={Fish Physiology and Biochemistry},
  year={2004},
  volume={17},
  pages={93-98}
}
The gonadotropin (GtH) IIβ mRNA levels in pituitary glands of male tilapia hybrids were proportional to the gonadosomatic index (GSI), while GtH Iβ was highest in fish with GSI of 0.56, but was lower in fish with more developed testes. In pituitary cells of immature fish, only GtH Iβ mRNA responded to testosterone (T) exposure (12–72h), rising nearly three-fold compared to the control cells. The stimulatory effect of T on GtH Iβ in these fish was also seen to be dose-related, but doses of 100… CONTINUE READING
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