The mRNA expression of SATB1 and SATB2 in human breast cancer

@article{Patani2009TheME,
  title={The mRNA expression of SATB1 and SATB2 in human breast cancer},
  author={Neill R Patani and Wen Jiang and Robert E. Mansel and Robert Frank Newbold and Kefah Mokbel},
  journal={Cancer Cell International},
  year={2009},
  volume={9},
  pages={18 - 18}
}
SATB1 is a nuclear protein that has been recently reported to be a 'genome organizer' which delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. In this study, the level of mRNA expression of SATB1 and SATB2 were assessed in normal and malignant breast tissue in a cohort of women with breast cancer and correlated to conventional clinico-pathological parameters. Breast cancer tissues (n… CONTINUE READING

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