The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice

@article{Hodge2005TheMA,
  title={The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice},
  author={Clyde W Hodge and Michael F. Miles and Amanda C. Sharko and Rebekah Ann Stevenson and Jennie R. Hillmann and Veronique Lepoutre and Joyce Besheer and Jason P. Schroeder},
  journal={Psychopharmacology},
  year={2005},
  volume={183},
  pages={429-438}
}
Many of the biochemical, physiological, and behavioral effects of ethanol are known to be mediated by ionotropic glutamate receptors. Emerging evidence implicates metabotropic glutamate receptors (mGluRs) in the biobehavioral effects of ethanol and other drugs of abuse, but there is little information regarding the role of mGluRs in the reinforcing effects of ethanol. Male C57BL/6J mice were trained to lever-press on a concurrent fixed ratio 1 schedule of ethanol (10% v/v) vs water… CONTINUE READING
54 Extracted Citations
74 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 54 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 74 references

Similar Papers

Loading similar papers…