The lysosomal cysteine proteases.

@article{Mcgrath1999TheLC,
  title={The lysosomal cysteine proteases.},
  author={M. Mcgrath},
  journal={Annual review of biophysics and biomolecular structure},
  year={1999},
  volume={28},
  pages={
          181-204
        }
}
  • M. Mcgrath
  • Published 1999
  • Medicine, Biology
  • Annual review of biophysics and biomolecular structure
A significant number of exciting papain-like cysteine protease structures have been determined by crystallographic methods over the last several years. This trove of data allows for an analysis of the structural features that empower these molecules as they efficiently carry out their specialized tasks. Although the structure of the paradigm for the family, papain, has been known for twenty years, recent efforts have reaped several structures of specialized mammalian enzymes. This review first… Expand
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