The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain

@article{Chan2018TheLT,
  title={The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain},
  author={Jia Pei Chan and Bernice H. Wong and Cheen Fei Chin and Dwight Lark Anolin Galam and Juat Chin Foo and Loo Chin Wong and Sujoy Ghosh and Markus R. Wenk and Amaury Cazenave-Gassiot and David L. Silver},
  journal={PLoS Biology},
  year={2018},
  volume={16}
}
Brain development requires a massive increase in brain lipogenesis and accretion of the essential omega-3 fatty acid docosahexaenoic acid (DHA). Brain acquisition of DHA is primarily mediated by the transporter Major Facilitator Superfamily Domain containing 2a (Mfsd2a) expressed in the endothelium of the blood-brain barrier (BBB) and other abundant cell types within the brain. Mfsd2a transports DHA and other polyunsaturated fatty acids (PUFAs) esterified to lysophosphatidylcholine (LPC-DHA… 

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