The lymphatic vasculature in disease

  title={The lymphatic vasculature in disease},
  author={Kari Alitalo},
  journal={Nature Medicine},
  • K. Alitalo
  • Published 1 November 2011
  • Biology, Medicine
  • Nature Medicine
Blood vessels form a closed circulatory system, whereas lymphatic vessels form a one-way conduit for tissue fluid and leukocytes. In most vertebrates, the main function of lymphatic vessels is to collect excess protein-rich fluid that has extravasated from blood vessels and transport it back into the blood circulation. Lymphatic vessels have an important immune surveillance function, as they import various antigens and activated antigen-presenting cells into the lymph nodes and export immune… 

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