The lupus erythematosus cell phenomenon: comparative analysis of antichromatin antibody specificity in lupus erythematosus cell-positive and -negative sera.

@article{Schett2000TheLE,
  title={The lupus erythematosus cell phenomenon: comparative analysis of antichromatin antibody specificity in lupus erythematosus cell-positive and -negative sera.},
  author={Georg Schett and Robert L Rubin and Guenter Steiner and H Hiesberger and Sd Muller and Josef Smolen},
  journal={Arthritis and rheumatism},
  year={2000},
  volume={43 2},
  pages={
          420-8
        }
}
OBJECTIVE To compare and investigate antihistone and antichromatin antibody responses as well as clinical variables in patients with systemic lupus erythematosus (SLE) who were either positive (LEC+) or negative (LEC-) for the lupus erythematosus (LE) cell phenomenon. METHODS The binding properties of LEC+ and LEC- SLE sera to chromatin-associated nuclear antigens (histones H1, H2A, H2B, H3, H4; complexes of H2A-H2B, [H2A-H2B]-DNA, H1-DNA; total and H1-stripped chromatin; native and denatured… CONTINUE READING
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