The lung is a site of platelet biogenesis and a reservoir for hematopoietic progenitors

Abstract

Platelets are critical for haemostasis, thrombosis, and inflammatory responses, but the events that lead to mature platelet production remain incompletely understood. The bone marrow has been proposed to be a major site of platelet production, although there is indirect evidence that the lungs might also contribute to platelet biogenesis. Here, by directly… (More)
DOI: 10.1038/nature21706

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