The low dose ACTH test in chronic fatigue syndrome and in health.

@article{Scott1998TheLD,
  title={The low dose ACTH test in chronic fatigue syndrome and in health.},
  author={Lucinda V Scott and S H Medbak and Timothy G Dinan},
  journal={Clinical endocrinology},
  year={1998},
  volume={48 6},
  pages={733-7}
}
OBJECTIVE A number of dynamic tests of the hypothalamic-pituitary-adrenal axis provide evidence for a mild central adrenal insufficiency in chronic fatigue syndrome (CFS). The 1 microgram adrenocorticotropin (ACTH) test has been proposed to be more sensitive than the standard 250 micrograms ACTH test in the detection of subtle pituitary-adrenal hypofunctioning. We aimed to establish whether the 1 microgram ACTH test would support such a dysregulation in CFS, and also, given the relative novelty… CONTINUE READING

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