The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6.

@article{Guiraldelli2008TheLA,
  title={The low affinity IgG receptor Fc gamma RIIB contributes to the binding of the mast cell specific antibody, mAb BGD6.},
  author={Michel Farchi Guiraldelli and Elsa H. Berenstein and Ana Cristina G. Grodzki and Reuben P. Siraganian and Maria C{\'e}lia Jamur and C. G. M. Oliver},
  journal={Molecular immunology},
  year={2008},
  volume={45 8},
  pages={
          2411-8
        }
}
The mast cell specific monoclonal antibody, mAb BGD6, is a mast cell lineage marker [Jamur, M.C., Grodzki, A.C., Berenstein, E.H., Hamawy, M.M., Siraganian, R.P., Oliver, C., 2005. Identification and characterization of undifferentiated mast cells in mouse bone marrow. Blood 105, 4282-4289]. In rat basophilic leukemia (RBL-2H3) cells, mAb BGD6 precipitates cell-surface proteins of approximately 110 and 40-60 kDa. An expression cloning strategy was used to identify proteins that interact with… CONTINUE READING

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