The long-term effects of probucol on serum lipid levels.

  title={The long-term effects of probucol on serum lipid levels.},
  author={Dorothy McCaughan},
  journal={Archives of internal medicine},
  volume={141 11},
Probucol, a serum cholesterol-lowering agent, was studied in a double-blind, placebo-controlled trial for one year in 118 hypercholesterolemic men. The mean decrease in the level of serum cholesterol in the probucol group (N = 88) from baseline for months 6 through 12 ranged from 16.2% to 20.9%. The mean decrease from baseline for the placebo-treated patients (N = 30) ranged from 5.2% to 12.7%. The difference between the groups was highly significant. At the end of this one-year trial, 61 of… CONTINUE READING