The long-term effect of tetrabenazine in the management of Huntington disease.

@article{Fasano2008TheLE,
  title={The long-term effect of tetrabenazine in the management of Huntington disease.},
  author={Alfonso Fasano and Federica Cadeddu and Arianna Guidubaldi and Carla Piano and Francesco Soleti and Paola Zinzi and Anna Rita Bentivoglio},
  journal={Clinical neuropharmacology},
  year={2008},
  volume={31 6},
  pages={313-8}
}
OBJECTIVES To enhance the knowledge on the long-term efficacy and safety of tetrabenazine (TBZ) in managing chorea. METHODS We analyzed 68 Huntington disease patients (mean disease duration, 55.8 +/- 34.7 months) who had been treated with TBZ for a mean period of 34.4 +/- 25.2 months (median, 34 months; mode, 48 months; range, 3-104 months). We measured the variation from pretreatment of the motor score of Unified Huntington's Disease Rating Scale at the first follow-up visit and at the… CONTINUE READING

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