The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma.

@article{Li2018TheLN,
  title={The long non-coding RNA SPRY4-IT1: An emerging player in tumorigenesis and osteosarcoma.},
  author={Zheng Li and Jianxiong Shen and Matthew T V Chan and William Ka Kei Wu},
  journal={Cell proliferation},
  year={2018}
}
Accumulating evidence from genome-wide analysis and functional studies has begun to unveil the important role of long non-coding RNAs (lncRNAs) in cancer development. The lncRNA SPRY4-IT1 is derived from an intron of SPRY4 gene and was originally reported to be upregulated in melanoma in which it functioned as an oncogene. Since this discovery, an… CONTINUE READING