The locus ordering problem.

@article{Edwards1987TheLO,
  title={The locus ordering problem.},
  author={Judge Harry Edwards},
  journal={Annals of human genetics},
  year={1987},
  volume={51 3},
  pages={
          251-8
        }
}
Studies of phenotypes defined by codominant alleles at two or more loci in three-generation families allow haplotypes to be deduced. These data are easily summarized by the Mendelian convention of upper and lower case, with case defining phase rather than nature. In two-generation families haplotypes may be inferred with high precision for closely linked loci even if an allele at one locus is recessive. Coding procedures are discussed and a simple solution to inferring the most likely order of… CONTINUE READING

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