The locus coeruleus and immediate-early genes in spontaneous and forced wakefulness.

@article{Tononi1994TheLC,
  title={The locus coeruleus and immediate-early genes in spontaneous and forced wakefulness.},
  author={Giulio Tononi and Maria Pompeiano and Chiara Cirelli},
  journal={Brain research bulletin},
  year={1994},
  volume={35 5-6},
  pages={589-96}
}
In this study, we mapped the expression of two immediate-early genes to examine the functional activation of the locus coeruleus and other regions of the rat brain after periods of spontaneous wakefulness or sleep and after sleep deprivation. c-fos and NGFI-A are two immediate-early genes that are rapidly induced by physiological stimuli and can be used as molecular markers of neural activation. We used immunocytochemical detection of Fos and NGFI-A proteins associated with double labeling for… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…