The location of MZF-1 at the telomere of human chromosome 19q makes it vulnerable to degeneration in aging cells.

@article{Hoffman1996TheLO,
  title={The location of MZF-1 at the telomere of human chromosome 19q makes it vulnerable to degeneration in aging cells.},
  author={Susan M.G Hoffman and Robert Hromas and Chris T Amemiya and Harvey W. Mohrenweiser},
  journal={Leukemia research},
  year={1996},
  volume={20 3},
  pages={281-3}
}
A zinc-finger gene encoding a transcription factor that regulates hematopoiesis, MZF-1, is located at the extreme end of the q arm of human chromosome 19. Several lines of evidence indicate that MZF-1 lies less than 20 kb from the subtelomeric repeat region of 19q. Telomeres are known to degenerate as cells age; disruption of MZF-1 due to telomeric… CONTINUE READING