The localization of the target antigens and antibodies in linear IgA disease is heterogeneous, and dependent on the methods used.

Abstract

Fifty-nine patients with linear IgA disease, 24 with onset in childhood and 35 with adult onset, were studied. Sera from all patients were tested by indirect immunofluorescence, using as substrates intact normal skin and normal skin which had been split through the lamina lucida region of the basement membrane zone by suction and by prolonged incubation… (More)

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