The local role of tumor necrosis factor alpha in the modulation of neutrophil function at sites of inflammation.


OBJECTIVE To examine the hypothesis that tumor necrosis factor alpha (TNF-alpha) is an important local modulator of neutrophil function in the inflammatory microenvironment. DESIGN In vitro studies of host defense. PATIENTS A volunteer sample of healthy subjects. INTERVENTION Exudative neutrophils were collected from skin-blister chambers and… (More)


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