The local injection of peritoneal macrophages induces neovascularization in rat ischemic hind limb muscles.

@article{Hirose2008TheLI,
  title={The local injection of peritoneal macrophages induces neovascularization in rat ischemic hind limb muscles.},
  author={Nobuyuki Hirose and Hironori Maeda and Morio Yamamoto and Yoshihiro Hayashi and Gwangrog Lee and Liyan Chen and Geethalakshmi Radhakrishnan and P. Yedukondala Rao and Shiro Sasaguri},
  journal={Cell transplantation},
  year={2008},
  volume={17 1-2},
  pages={
          211-22
        }
}
Macrophages play a pivotal role in the development of newly formed vascular networks, in addition to their normal immunological functions. This research focuses on peritoneal macrophages as a novel source in cell implantation therapy for ischemic diseases. In this study, production of angiogenic growth factors by peritoneal macrophages and its in vivo effect of neovascularization were evaluated. Mononuclear cells from the peritoneal cavity (P-MNCs) enriched with macrophages were isolated and… CONTINUE READING
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