The local effects of systemic digoxin on the cutaneous microcirculation

Abstract

Objective: The present study was designed to explore whether digoxin modifies cutaneous vascular responses to an endothelium-dependent vasodilator (acetylcholine) or to the vasoconstrictor norepinephrine. Methods: In a double-blind cross-over study 12 healthy subjects received digoxin 0.25 mg twice daily (after adequate loading doses) or placebo for a total… (More)
DOI: 10.1007/s002280050627

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