The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

@inproceedings{Liang2015TheLH,
  title={The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer},
  author={Wei-cheng Liang and W. M. Fu and C M Wong and Yan Wang and Wei-mao Wang and Guoxin Hu and Li Zhang and Li-Jia Xiao and David Chi-Cheong Wan and Jinfang Zhang and Mary Miu Yee Waye},
  booktitle={Oncotarget},
  year={2015}
}
Recently, the long non-coding RNA (lncRNA) H19 has been identified as an oncogenic gene in multiple cancer types and elevated expression of H19 was tightly linked to tumorigenesis and cancer progression. However, the molecular basis for this observation has not been characterized in colorectal cancer (CRC) especially during epithelial to mesenchymal transition (EMT) progression. In our studies, H19 was characterized as a novel regulator of EMT in CRC. We found that H19 was highly expressed in… CONTINUE READING
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