The living factory: In vivo Production of N-acetyllactosamine containing carbohydrates in E. coli

@article{Bettler2004TheLF,
  title={The living factory: In vivo Production of N-acetyllactosamine containing carbohydrates in E. coli},
  author={E. Bettler and E. Samain and V. Chazalet and C. Bosso and A. Heyraud and D. Joziasse and W. Wakarchuk and A. Imberty and R. Geremia},
  journal={Glycoconjugate Journal},
  year={2004},
  volume={16},
  pages={205-212}
}
Scientific and commercial interest in oligosaccharides is increasing, but their availability is limited as production relies on chemical or chemo-enzymatic synthesis. In search for a more economical, alternative procedure, we have investigated the possibility of producing specific oligosaccharides in E. coli that express the appropriate glycosyltransferases. The Azorhizobium chitin pentaose synthase NodC (a β(1,4)GlcNAc-transferase), and the Neisseria β(1,4)galactosyltransferase LgtB, were co… Expand
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