The liver as a major site of immunological elimination of murine trypanosome infection, demonstrated with the liver perfusion model.

@article{Albright1990TheLA,
  title={The liver as a major site of immunological elimination of murine trypanosome infection, demonstrated with the liver perfusion model.},
  author={Julia W. Albright and Gary W. Long and Joseph F. Albright},
  journal={Infection and immunity},
  year={1990},
  volume={58 6},
  pages={1965-70}
}
The isolated liver perfusion model has been used to investigate immunological elimination of bacteria and yeasts but not for analysis of mechanisms of immunological destruction of extracellular parasitic protozoa. Extracellular trypanosomes are eliminated primarily through antibody (and complement?)-promoted hepatic (Kupffer cell) uptake and destruction. We studied the suitability of the isolated liver model system for analyzing the mechanism of immune elimination of mouse-specific Trypanosoma… CONTINUE READING

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Binding of Trypanosoma congolense to the walls of small blood vessels.

The Journal of protozoology • 1978
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