The lipid raft hypothesis revisited--new insights on raft composition and function from super-resolution fluorescence microscopy.

@article{Owen2012TheLR,
  title={The lipid raft hypothesis revisited--new insights on raft composition and function from super-resolution fluorescence microscopy.},
  author={Dylan M. Owen and Astrid Magenau and David J. Williamson and Katharina Gaus},
  journal={BioEssays : news and reviews in molecular, cellular and developmental biology},
  year={2012},
  volume={34 9},
  pages={739-47}
}
Recently developed super-resolution microscopy techniques are changing our understanding of lipid rafts and membrane organisation in general. The lipid raft hypothesis postulates that cholesterol can drive the formation of ordered domains within the plasma membrane of cells, which may serve as platforms for cell signalling and membrane trafficking. There is now a wealth of evidence for these domains. However, their study has hitherto been hampered by the resolution limit of optical microscopy… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 85 references

Fluorescent probes for superresolution imaging of lipid domains on the plasma membrane

H Mizuno, M Abe, P Dedecker, A Makino
Chem Sci • 2011
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