The linkage between protein folding and functional cooperativity: two sides of the same coin?

Abstract

During the course of their biological function, proteins undergo different types of structural rearrangements ranging from local to large-scale conformational changes. These changes are usually triggered by their interactions with small-molecular-weight ligands or other macromolecules. Because binding interactions occur at specific sites and involve only a… (More)

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Cite this paper

@article{Luque2002TheLB, title={The linkage between protein folding and functional cooperativity: two sides of the same coin?}, author={Irene Luque and Stephanie A Leavitt and Ernesto Freire}, journal={Annual review of biophysics and biomolecular structure}, year={2002}, volume={31}, pages={235-56} }