The linear no-threshold response: why not linearity?

  title={The linear no-threshold response: why not linearity?},
  author={Warren K. Sinclair},
  journal={Medical physics},
  volume={25 3},
          285-90; discussion 300
ICRP and NCRP recommend risk coefficients for use in radiation protection that are based on a linear quadratic response in the low dose region. This is a derivative of the linear no threshold (LNT) hypothesis with allowance for low dose and dose rate effects. The risk coefficients are derived from the Lifespan Study of the A-bomb survivors but are supported by many other epidemiological studies some, such as occupational, at low doses. Nevertheless, the risk coefficients are uncertain and range… CONTINUE READING