The limited role of the glomerular endothelial cell glycocalyx as a barrier to transglomerular albumin transport.

@article{Comper2014TheLR,
  title={The limited role of the glomerular endothelial cell glycocalyx as a barrier to transglomerular albumin transport.},
  author={Wayne D. Comper},
  journal={Connective tissue research},
  year={2014},
  volume={55 1},
  pages={2-7}
}
For over 50 years, the glomerular filter has been thought to exert an uniquely significant barrier to the transport of albumin. The glomerular endothelial cell glycocalyx is considered to contribute to this important barrier restriction. In renal disease, structural alterations to this layer have been associated with albuminuria. It appears however the claims of the influence of this barrier have been overstated. The behaviour of albumin in systems that model the glycocalyx has been studied… CONTINUE READING