The limit of plausibility for predictors of response: application to biventricular pacing.

@article{Nijjer2012TheLO,
  title={The limit of plausibility for predictors of response: application to biventricular pacing.},
  author={Sukhjinder Singh Nijjer and Punam A. Pabari and Berthold P. Stegemann and Vittorio G. Palmieri and F. H. Ram{\'i}rez Leyva and Cecilia M Linde and Nick Freemantle and Justin E. Davies and Alun D. Hughes and Darrel P. Francis},
  journal={JACC. Cardiovascular imaging},
  year={2012},
  volume={5 10},
  pages={1046-65}
}
OBJECTIVES We sought a method for any reader to quantify the limit, imposed by variability, to sustainably observable R(2) between any baseline predictor and response marker. We then apply this to echocardiographic measurements of mechanical dyssynchrony and response. BACKGROUND Can mechanical dyssynchrony markers strongly predict ventricular remodeling by biventricular pacing (cardiac resynchronization therapy)? METHODS First, we established the mathematical depression of observable R(2… CONTINUE READING
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