The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells.

Abstract

We examined the effects of a variety of ligands/activators of the peroxisome proliferator-activated receptor (PPAR) on the expression of the superoxide scavenger enzyme, Cu2+,Zn2+-superoxide dismutase (CuZn-SOD), and the superoxide generating enzyme nicotinamide adenine dinucleotide phosphate (reduced form) (NADPH) oxidase in primary cultures of human… (More)

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@article{Inoue2001TheLF, title={The ligands/activators for peroxisome proliferator-activated receptor alpha (PPARalpha) and PPARgamma increase Cu2+,Zn2+-superoxide dismutase and decrease p22phox message expressions in primary endothelial cells.}, author={Itsuro Inoue and Shin G Goto and T. Matsunaga and T. Nakajima and Takanori Awata and S. Hokari and Toshiya Komoda and S. Katayama}, journal={Metabolism: clinical and experimental}, year={2001}, volume={50 1}, pages={3-11} }